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1

Employment of adult mammalian primary cells in toxicology: In vivo and in vitro genotoxic effects of environmentally significant N-nitrosodialkylamines in cells of the liver, lung, and kidney

Beatrice L. Pool, S. Y. Brendler, U. M. Liegibel, A. Tompa, P. Schmezer

Journal:

Environmental and Molecular Mutagenesis

Année:

1990

Langue:

english

Fichier:

PDF, 1.00 MB

english, 1990

2

Detection of genotoxic effects in human gastric and nasal mucosa cells isolated from biopsy samples

Dr. Beatrice L. Pool-Zobel, Natalie Lotzmann, Martin Knoll, Frank Kuchenmeister, Renate Lambertz, Ullrich Leucht, Hans-GÜNther Schröder, Peter Schmezer

Journal:

Environmental and Molecular Mutagenesis

Année:

1994

Langue:

english

Fichier:

PDF, 1.75 MB

english, 1994

3

An investigation of the DNA-damaging ability of benzene and its metabolites in human lymphocytes, using the comet assay

Dr. D. Anderson, T.-W. Yu, P. Schmezer

Journal:

Environmental and Molecular Mutagenesis

Année:

1995

Langue:

english

Fichier:

PDF, 775 KB

english, 1995

4

Cells of different tissues for in vitro and in vivo studies in toxicology: Compilation of isolation methods

Brendler-Schwaab, S.Y., Schmezer, P., Liegibel, U., Weber, S., Michalek, K., Tompa, A., Pool-Zobel, B.L.

Journal:

Toxicology in Vitro

Année:

1994

Langue:

english

Fichier:

PDF, 1.77 MB

english, 1994

5

Effect of long-term inhalation of N-nitroso-dimethyl amine (NDMA) and SO2/NOx in rats

Klein, R.G., Janowsky, I., Schmezer, P., Hermann, R., Spiegelhalder, B., Zeller, W.J., Pool, B.L.

Journal:

Experimental Pathology

Année:

1989

Langue:

english

Fichier:

PDF, 779 KB

english, 1989

6

Detection of mutations in bacteria and of DNA damage and amplified DNA sequences in mammalian cells as a systematic test strategy for elucidating biological activities of chemical carcinogens

Pool, B.L., Eisenbrand, G., Preussmann, R., Schlehofer, J.R., Schmezer, P., Weber, H., Wiessler, M.

Journal:

Food and Chemical Toxicology

Année:

1986

Langue:

english

Fichier:

PDF, 687 KB

english, 1986

7

XRCC1 Polymorphism Associated With Late Toxicity After Radiation Therapy in Breast Cancer Patients

Seibold, Petra, Behrens, Sabine, Schmezer, Peter, Helmbold, Irmgard, Barnett, Gillian, Coles, Charlotte, Yarnold, John, Talbot, Christopher J., Imai, Takashi, Azria, David, Koch, C. Anne, Dunning, Ali

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

2015

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2015

8

DNA damage in human whole blood caused by radiopharmaceuticals evaluated by the comet assay

Schmeiser, Heinz H, Muehlbauer, Karl-Rudolf, Mier, Walter, Baranski, Ann-Christin, Neels, Oliver, Dimitrakopoulou-Strauss, Antonia, Schmezer, Peter, Kratochwil, Clemens, Bruchertseifer, Frank, Morgens

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 213 KB

english, 2019

9

hOGG1 polymorphism and loss of heterozygosity (LOH): Significance for lung cancer susceptibility in a caucasian population

H. Wikman, A. Risch, F. Klimek, P. Schmezer, B. Spiegelhalder, H. Dienemann, K. Kayser, V. Schulz, P. Drings, H. Bartsch

Journal:

International Journal of Cancer

Année:

2000

Langue:

english

Fichier:

PDF, 95 KB

english, 2000

10

Altered DNA repair capacity and bleomycin sensitivity as risk markers for non-small cell lung cancer

N. Rajaee-Behbahani, P. Schmezer, A. Risch, W. Rittgen, K.W. Kayser, H. Dienemann, V. Schulz, P. Drings, S. Thiel, H. Bartsch

Journal:

International Journal of Cancer

Année:

2001

Langue:

english

Fichier:

PDF, 93 KB

english, 2001

11

Assay-specific genotoxicity of N-nitrosodibenzylamine to the rat liver in vivo

P. Schmezer, B. L. Pool, P. A. Lefevre, R. D. Callander, F. Ratpan, H. Tinwell, J. Ashby

Journal:

Environmental and Molecular Mutagenesis

Année:

1990

Langue:

english

Fichier:

PDF, 677 KB

english, 1990

12

Down-regulation of tumor suppressor a kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms

Benjamin Goeppert, Peter Schmezer, Céline Dutruel, Christopher Oakes, Marcus Renner, Marco Breinig, Arne Warth, Monika Nadja Vogel, Michel Mittelbronn, Arianeb Mehrabi, Georg Gdynia, Roland Penzel, Th

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 580 KB

english, 2010

13

Reduced poly(ADP-ribosyl)ation in lymphocytes of laryngeal cancer patients: Results of a case-control study

Nahid Rajaee-Behbahani, Peter Schmezer, Heribert Ramroth, Alexander Bürkle, Helmut Bartsch, Andreas Dietz, Heiko Becher

Journal:

International Journal of Cancer

Année:

2002

Langue:

english

Fichier:

PDF, 76 KB

english, 2002

14

Myeloperoxidase (MPO) genotype and lung cancer histologic types: The MPO −463 A allele is associated with reduced risk for small cell lung cancer in smokers

Heike Dally, Kai Gassner, Birgit Jäger, Peter Schmezer, Bertold Spiegelhalder, Lutz Edler, Peter Drings, Hendrik Dienemann, Volker Schulz, Klaus Kayser, Helmut Bartsch, Angela Risch

Journal:

International Journal of Cancer

Année:

2002

Langue:

english

Fichier:

PDF, 105 KB

english, 2002

15

Occupation, exposure to polycyclic aromatic hydrocarbons and laryngeal cancer risk

Heiko Becher, Heribert Ramroth, Wolfgang Ahrens, Angela Risch, Peter Schmezer, Andreas Dietz

Journal:

International Journal of Cancer

Année:

2005

Langue:

english

Fichier:

PDF, 113 KB

english, 2005

16

In vitro radiation-induced expression of XPC mRNA as a possible biomarker for developing adverse reactions during radiotherapy

Katrin Wiebalk, Peter Schmezer, Silke Kropp, Jenny Chang-Claude, Oktay Celebi, Jürgen Debus, Helmut Bartsch, Odilia Popanda

Journal:

International Journal of Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 104 KB

english, 2007

17

Genetic predictors of long-term toxicities after radiation therapy for breast cancer

Nataliya Kuptsova, Jenny Chang-Claude, Silke Kropp, Irmgard Helmbold, Peter Schmezer, Dietrich von Fournier, Wulf Haase, Marie Luise Sautter-Bihl, Frederik Wenz, Kenan Onel, Christine B. Ambrosone

Journal:

International Journal of Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 99 KB

english, 2008

18

Laryngeal cancer risk associated with smoking and alcohol consumption is modified by genetic polymorphisms in ERCC5, ERCC6 and RAD23B but not by polymorphisms in five other nucleotide excision repair genes

Rashda Abbasi, Heribert Ramroth, Heiko Becher, Andreas Dietz, Peter Schmezer, Odilia Popanda

Journal:

International Journal of Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 122 KB

english, 2009

19

Polymorphisms in oxidative stress-related genes and postmenopausal breast cancer risk

Petra Seibold, Rebecca Hein, Peter Schmezer, Per Hall, Jianjun Liu, Norbert Dahmen, Dieter Flesch-Janys, Odilia Popanda, Jenny Chang-Claude

Journal:

International Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 236 KB

english, 2011

20

Cytochrome P450 2a of nasal epithelium: Regulation and role in carcinogen metabolism

Jean-Claude Béréziat, Francoise Raffalli, Peter Schmezer, Eva Frei, Olivier Geneste, Matti A. Lang

Journal:

Molecular Carcinogenesis

Année:

1995

Langue:

english

Fichier:

PDF, 885 KB

english, 1995

21

Image analysis of hepatocyte nuclei in assessing di(2-ethylhexyl)phthalate effects eluding detection by conventional microscopy

Dymitr Komitowski, Peter Schmezer, Bertold Schmitt, Shuhei Muto

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 472 KB

english, 1986

22

DNA damaging capability of hematoporphyrin towards DNAs of various accessibilities

M. Egyeki, K. Tóth, W. Waldeck, P. Schmezer, J. Langowski, G. Csík

Journal:

Journal of Photochemistry and Photobiology B: Biology

Année:

2006

Langue:

english

Fichier:

PDF, 289 KB

english, 2006

23

Preliminary assessment of the skin sensitizing activity of selected rodent carcinogens using the local lymph node assay

E.Vicky Warbrick, Rebecca J Dearman, John Ashby, Peter Schmezer, Ian Kimber

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 75 KB

english, 2001

24

Laryngeal mucosa of head and neck cancer patients shows increased DNA damage as detected by single cell microgel electrophoresis

P Schmezer, T Rupprecht, M Tisch, H Maier, H Bartsch

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 84 KB

english, 2000

25

Radiation-induced DNA damage and repair in lymphocytes from breast cancer patients and their correlation with acute skin reactions to radiotherapy

Odilia Popanda, Reinhard Ebbeler, Dorothee Twardella, Irmgard Helmbold, Florian Gotzes, Peter Schmezer, Heinz Walter Thielmann, Dietrich von Fournier, Wulf Haase, Marie Luise Sautter-Bihl, Frederik We

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

2003

Langue:

english

Fichier:

PDF, 345 KB

english, 2003

26

Systemic genotoxic effects of tobacco-related nitrosamines following oral and inhalational administration to Sprague-Dawley rats

B. L. Pool-Zobel, R. G. Klein, U. M. Liegibel, F. Kuchenmeister, S. Weber, P. Schmezer

Journal:

Journal of Molecular Medicine

Année:

1992

Langue:

english

Fichier:

PDF, 641 KB

english, 1992

27

DNA Damage from Endogenous Processes, Workshop

H. Bartsch, A. Risch, P. Schmezer, I. Velic, M. Schwarz

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

1997

Langue:

english

Fichier:

PDF, 305 KB

english, 1997

28

Suberoylanilide hydroxamic acid affects γH2AX expression in osteosarcoma, atypical teratoid rhabdoid tumor and normal tissue cell lines after irradiation

C. Blattmann, S. Oertel, M. Thiemann, K.J. Weber, P. Schmezer, O. Zelezny, R. Lopez Perez, A.E. Kulozik, J. Debus, V. Ehemann

Journal:

Strahlentherapie und Onkologie

Année:

2012

Langue:

english

Fichier:

PDF, 667 KB

english, 2012

29

Epigenetische Aspekte bei Karzinomen der Kopf-Hals-Region

P. Schmezer, C. Plass

Journal:

Année:

2008

Langue:

german

Fichier:

PDF, 399 KB

german, 2008

30

Genotoxicity studies on permethrin, DEET and diazinon in primary human nasal mucosal cells

M. Tisch, P. Schmezer, M. Faulde, A. Groh, Heinz Maier

Journal:

European Archives of Oto-Rhino-Laryngology

Année:

2002

Langue:

english

Fichier:

PDF, 103 KB

english, 2002

31

Carcinogenicity assays of wood dust and wood additives in rats exposed by long-term inhalation

R. G. Klein, P. Schmezer, F. Amelung, H.-G. Schroeder, W. Woeste, J. Wolf

Journal:

International Archives of Occupational and Environmental Health

Année:

2001

Langue:

english

Fichier:

PDF, 138 KB

english, 2001

32

Association betweenTP53andp21genetic polymorphisms and acute side effects of radiotherapy in breast cancer patients

Xiang-Lin Tan, Odilia Popanda, Christine B. Ambrosone, Silke Kropp, Irmgard Helmbold, Dietrich von Fournier, Wulf Haase, Marie Luise Sautter-Bihl, Frederik Wenz, Peter Schmezer, Jenny Chang-Claude

Journal:

Breast Cancer Research and Treatment

Année:

2006

Langue:

english

Fichier:

PDF, 293 KB

english, 2006

33

Predictive factors for late normal tissue complications following radiotherapy for breast cancer

Carmen Lilla, Christine B. Ambrosone, Silke Kropp, Irmgard Helmbold, Peter Schmezer, Dietrich von Fournier, Wulf Haase, Marie-Luise Sautter-Bihl, Frederik Wenz, Jenny Chang-Claude

Journal:

Breast Cancer Research and Treatment

Année:

2007

Langue:

english

Fichier:

PDF, 183 KB

english, 2007

34

Polymorphisms in three base excision repair genes and breast cancer risk in Thai women

Suleeporn Sangrajrang, Peter Schmezer, Iris Burkholder, Peter Waas, Paolo Boffetta, Paul Brennan, Helmut Bartsch, Surapon Wiangnon, Odilia Popanda

Journal:

Breast Cancer Research and Treatment

Année:

2008

Langue:

english

Fichier:

PDF, 237 KB

english, 2008

35

Epigenetically mediated downregulation of the differentiation-promoting chaperon protein CRABP2 in astrocytic gliomas

Benito Campos, Rolf Warta, Jittiporn Chaisaingmongkol, Lea Geiselhart, Odilia Popanda, Christian Hartmann, Andreas von Deimling, Andreas Unterberg, Christoph Plass, Peter Schmezer, Christel Herold-Men

Journal:

International Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2012

36

Germline variants of base excision repair genes and breast cancer: A polymorphism in DNA polymerase gamma modifies gene expression and breast cancer risk

Odilia Popanda, Petra Seibold, Ivaylo Nikolov, Christopher C. Oakes, Barbara Burwinkel, Sebastian Hausmann, Dieter Flesch-Janys, Christoph Plass, Jenny Chang-Claude, Peter Schmezer

Journal:

International Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 321 KB

english, 2012

37

Determination of DNA single strand breaks and selective DNA amplification by N-nitrodimethylamine and analogs, and estimation of the indicator cells' metabolic capacities

E. Frei, B. L. Pool, H. R. Glatt, I. Gemperlein-Mertes, F. Oesch, J. R. Schlehofer, P. Schmezer, H. Weber, M. Wiessler

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

1986

Langue:

english

Fichier:

PDF, 578 KB

english, 1986

38

Quantitative analysis of the early changes of hepatocyte nuclei after treating Syrian golden hamsters with Di(2-ethylhexyl)phthalate

Dymitr Komitowski, Peter Schmezer, Bertold Schmitt, Volker Ehemann, Shuhei Muto

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

1986

Langue:

english

Fichier:

PDF, 1.32 MB

english, 1986

39

Carcinogenicity of small doses of inhaled N-nitrosoacetoxymethyl-N-methylamine in Syrian golden hamsters

R. G. Klein, P. Schmezer, D. Komitowski

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

1986

Langue:

english

Fichier:

PDF, 583 KB

english, 1986

40

Mutagenic and genotoxic activities of extracts derived from the cooked and raw edible mushroomAgancus bisporus

B. L. Pool-Zobel, P. Schmezer, Y. Sinrachatanant, F. Kliagasioglu, K. Reinhart, R. Martin, P. Klein, A. R. Tricker

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

1990

Langue:

english

Fichier:

PDF, 600 KB

english, 1990

41

Genotoxic activities of benzamidine and itsN-hydroxylated metabolite benzamidoxime inSalmonella typhimuriumand mammalian cells

B. Clement, P. Schmezer, H. Weber, J. R. Schlehofer, S. Schmitt, B. L. Pool

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

1988

Langue:

english

Fichier:

PDF, 619 KB

english, 1988

42

Human epithelial cells from the upper aerodigestive tract show different susceptibility to genotoxic carcinogens

U. Harréus, P. Schmezer, H. Maier, F. Kuchenmeister, H. Bartsch

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

1995

Langue:

english

Fichier:

PDF, 145 KB

english, 1995

43

The non-genotoxicity to rodents of the potent rodent bladder carcinogens o-anisidine and p-cresidine

J. Ashby, P.A. Lefevre, H. Tinwell, G. Brunborg, P. Schmezer, B. Pool-Zobel, R. Shanu-Wilson, J.A. Holme, E.J. Soderlund, D. Gulati, J.P. Wojciechowski

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1991

Langue:

english

Fichier:

PDF, 960 KB

english, 1991

44

The single cell gel electrophoresis assay (comet assay): A European review

V.J. McKelvey-Martin, M.H.L. Green, P. Schmezer, B.L. Pool-Zobel, M.P. De Méo, A. Collins

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1993

Langue:

english

Fichier:

PDF, 1.51 MB

english, 1993

45

Tissue-specific induction of mutations by streptozotocin in vivo

Peter Schmezer, Claudia Eckert, Ute M. Liegibel

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1994

Langue:

english

Fichier:

PDF, 355 KB

english, 1994

46

The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay

D. Anderson, T.-W. Yu, B.J. Phillips, P. Schmezer

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1994

Langue:

english

Fichier:

PDF, 709 KB

english, 1994

47

Induction of selective DNA amplification by carcinogens/mutagens: Comparison to the S. thypuimurium mutagenicity test and to the hepatocyte/DNA single strand break assay

B.L. Pool, H. Weber, P. Schmezer, J.R. Schlenhofer

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Année:

1986

Langue:

english

Fichier:

PDF, 183 KB

english, 1986

48

In vitro/in vivo studies on the toxic and genotoxic properties of air pollutants, alone and combined with carcinogens

B.L. Pool, S. Brendler, R.G. Klein, P. Schmezer, W.J. Zeller

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Année:

1988

Langue:

english

Fichier:

PDF, 89 KB

english, 1988

49

(Geno-)toxicokinetics of DNA-damaging N-nitrosamines in the rat

P. Schmezer, S.Y. Brendler, A. Tompa, B.L. Pool

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Année:

1990

Langue:

english

Fichier:

PDF, 92 KB

english, 1990

50

Mixed disulfides from the antimutagens/anticarcinogens disulfiram and MESNA: synthesis, biochemical and biological effects

B. Bertram, B.H. Lee, A. Rajca, M. Wiessler, P. Schmezer, B.L. Pool

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Année:

1990

Langue:

english

Fichier:

PDF, 183 KB

english, 1990